Mutation Information
Mutation Site
|
L229F |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
RT |
Genotype/Subtype
|
B;C;D |
Relevant Drug
|
lamivudine (LAM) |
Country
|
China;India |
Literature Information
PubMed PMID
|
29713126
|
Published Year
|
2018 |
Journal
|
World journal of gastroenterology |
Title
|
Naturally occurring hepatitis B virus reverse transcriptase mutations related to potential antiviral drug resistance and liver disease progression. |
Author
|
Choi YM,Lee SY,Kim BJ |
Evidence
|
Recently, it has been proven through in vitro and in vivo experiments that several putative or pretreatment mutations, including rtL229F, rtS13T, and rtI233V, can also contribute to the development of drug resistance
|
|
|