Mutation Information
Mutation Site
|
M204V |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
RT |
Relevant Drug
|
lamivudine (LAM) |
Literature Information
PubMed PMID
|
11938042
|
Disease
|
Chronic hepatitis B
|
Published Year
|
2002 |
Journal
|
Gastroenterologie clinique et biologique |
Title
|
Lamivudine therapy of chronic hepatitis B in three groups of patients: non transplanted patients, liver recipients, and kidney recipients. |
Author
|
Schvoerer E,Kabissa I,Cotto E,Jouvencel AC,Balabaud C,De Ledinghen V,Couzigou P,Quinton A,Schvoerer C,Lafon ME,Fleury H,Bernard PH |
Evidence
|
After the development of lamivudine resistance, mutations rtM204V and rtL180M were detected in all studied patients, mutation rtM207I in one, with similar results from traditional nucleotide sequencing and a commercial line probe assay.
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