|
Mutation Information
|
Mutation Site
|
M250I |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Genotype/Subtype
|
D/D4 |
|
Relevant Drug
|
entecavir (ETV) |
|
Country
|
India |
Literature Information
|
PubMed PMID
|
23918533
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2013 |
|
Journal
|
Journal of medical virology |
|
Title
|
Hepatitis B virus reverse transcriptase mutations in treatment Naïve chronic hepatitis B patients. |
|
Author
|
Singla B,Chakraborti A,Sharma BK,Kapil S,Chawla YK,Arora SK,Das A,Dhiman RK,Duseja A |
|
Evidence
|
The known primary drug resistance mutations rtS202R and rtM250I that are responsible for ETV resistance were found in one patient.
|
|
|
HBV Mutation Detail Information