Mutation Information
Mutation Site
|
Y257W |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
RT |
Combined Mutation
|
rt.E271H+rt.I266V+rt.S259T+rt.Y257W+rt.V253I+rt.F221Y+rt.L217R+rt.M204V+rt.L180M+rt.I163V+rt.R153W+rt.F151Y+rt.F122N+rt.V103I;rt.Q267H+rt.Y257W+rt.Q215S+rt.R153W;rt.E271H+rt.I266V+rt.S259T+rt.Y257W+rt.V253I+rt.F221Y+rt.M204V+rt.L180M+rt.V173L+rt.I163V+rt.R153W+rt.F151Y+rt.L145M+rt.V142D;rt.Y257W+rt.N238A+rt.P237T+rt.Q215S+rt.V214A+rt.M204V+rt.L180M+rt.R153W |
Genotype/Subtype
|
D |
Relevant Drug
|
lamivudine (LAM) |
Country
|
Rome |
Literature Information
PubMed PMID
|
19442845
|
Disease
|
Chronic hepatitis B
|
Published Year
|
2009 |
Journal
|
Journal of virological methods |
Title
|
A sensitive direct sequencing assay based on nested PCR for the detection of HBV polymerase and surface glycoprotein mutations. |
Author
|
Vincenti D,Solmone M,Garbuglia AR,Iacomi F,Capobianchi MR |
Evidence
|
Table 1
|
|
|