HBV Mutation Detail Information

> N236T Search Result

Mutation Information

Mutation Site	N236T
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Relevant Drug	adefovir (ADV)

Literature Information

PubMed PMID	22505793
Published Year	2011
Journal	International journal of current chemistry
Title	Hepatitis B Virus genotypic differences map structurally close to NRTI resistance hot spots.
Author	Michailidis E,Singh K,Kirby KA,Hachiya A,Yoo W,Hong SP,Kim SO,Folk WR,Sarafianos SG
Evidence	RT residues 236, 237 and 238 are important for two reasons: first, they are ADV resistance sites (N236T, P237H, and N238H) (Table 1) and also vary among different genotypes in treatment-naïve patients (residues 237, 238).

Contents
Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation