Mutation Information
Mutation Site
|
V555I |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
P |
Relevant Drug
|
lamivudine (LAM);famciclovir (FCV) |
Literature Information
PubMed PMID
|
10655370
|
Disease
|
Chronic hepatitis B
|
Published Year
|
2000 |
Journal
|
Journal of clinical microbiology |
Title
|
Line probe assay for monitoring drug resistance in hepatitis B virus-infected patients during antiviral therapy. |
Author
|
Stuyver L,Van Geyt C,De Gendt S,Van Reybroeck G,Zoulim F,Leroux-Roels G,Rossau R |
Evidence
|
Previously genotyped HBV strains isolated from treated and untreated patients were amplified with primers specific for the HBV polymerase region from amino acids 465 to 562. A set of 38 highly specific oligonucleotide probes covering three different codon positions, L528M, M552V/I, and V/L/M555I, were selected.
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