|
Mutation Information
|
Mutation Site
|
M204I |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
adefovir (ADV) |
|
Country
|
Italy |
Literature Information
|
PubMed PMID
|
23026293
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2012 |
|
Journal
|
Antiviral research |
|
Title
|
Genotype-specific mutations in the polymerase gene of hepatitis B virus potentially associated with resistance to oral antiviral therapy. |
|
Author
|
Mirandola S,Sebastiani G,Rossi C,Velo E,Erne EM,Vario A,Tempesta D,Romualdi C,Campagnolo D,Alberti A |
|
Evidence
|
And rtM204I (60%) in LAM+ADV group while LAM-treated patients showed a preference of rtM204V
|
|
|
HBV Mutation Detail Information