|
Mutation Information
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Mutation Site
|
L491M |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
P |
Literature Information
|
PubMed PMID
|
10682123
|
|
Disease
|
HBV infection
|
|
Published Year
|
1999 |
|
Journal
|
Antiviral therapy |
|
Title
|
Analysis of hepatitis B virus quasispecies changes during emergence and reversion of lamivudine resistance in liver transplantation. |
|
Author
|
Cane PA,Mutimer D,Ratcliffe D,Cook P,Beards G,Elias E,Pillay D |
|
Evidence
|
Apparently complete reversion back to wild-type polymerase at codons 526, 550 and 565 occurred within 148 days of stopping famciclovir but the revertant virus also showed F567Y and L491M changes.
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HBV Mutation Detail Information