|
Mutation Information
|
Mutation Site
|
G174C |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
lamivudine (LAM) |
Literature Information
|
PubMed PMID
|
17666334
|
|
Published Year
|
2007 |
|
Journal
|
Nan fang yi ke da xue xue bao = Journal of Southern Medical University |
|
Title
|
[Construction of whole-genome lamivudine-resistant hepatitis B virus mutant and its replication and expression in HepG2 cells]. |
|
Author
|
Sun J,Wang C,Wen SJ,Wang ZH,Hou JL |
|
Evidence
|
The replication of the 3 mutant plasmids with rtG172E, rtG174C and rtG172E/rtG174C mutation decreased significantly in comparison with the wild-type virus.
|
|
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HBV Mutation Detail Information