HBV Mutation Detail Information

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Mutation Information

Mutation Site	F221Y
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Combined Mutation	rt.L229V+rt.F221Y;rt.L229M+rt.F221Y;rt.N238H+rt.I224V+rt.F221Y
Genotype/Subtype	B;C
Relevant Drug	lamivudine (LAM);adefovir dipivoxil (ADV);entecavir (ETV)
Country	China

Literature Information

PubMed PMID	31147594
Disease	HBV infection
Published Year	2019
Journal	Scientific reports
Title	Potential resistant mutations within HBV reverse transcriptase sequences in nucleos(t)ide analogues-experienced patients with hepatitis B virus infection.
Author	Zhang X,Chen X,Wei M,Zhang C,Xu T,Liu L,Xu Z
Evidence	Inthisstudy,non-classicalmutationswereobservedin29patientswhosufferingfromvirologicalbreakthroughandwithoutclassicalmutations(Table.4)at9sites(V191I,V207I/M,S213T,E218D,F221Y,I224V,L229V,N/H238andR242D).

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation