|
Mutation Information
|
Mutation Site
|
M204I |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Genotype/Subtype
|
A;D |
|
Relevant Drug
|
lamivudine (LAM) |
|
Country
|
Ugandan |
Literature Information
|
PubMed PMID
|
26386408
|
|
Disease
|
HBV-HIV coinfection
|
|
Published Year
|
2015 |
|
Journal
|
Transactions of the Royal Society of Tropical Medicine and Hygiene |
|
Title
|
Epidemiology of HBV infection in a cohort of Ugandan HIV-infected patients and rate and pattern of lamivudine-resistant HBV infection in patients receiving antiretroviral therapy. |
|
Author
|
Calisti G,Muhindo R,Boum Y 2nd,Wilson LA,Foster GM,Geretti AM,Bhagani S |
|
Evidence
|
Of the 23 patients in whom HBV-DNA sequencing was successful, 17 had lamivudine-resistant HBV strains harbouring rtM204V/I mutations accompanied by secondary/compensatory mutations.
|
|
|
HBV Mutation Detail Information