|
Mutation Information
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Mutation Site
|
F221Y |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
Literature Information
|
PubMed PMID
|
12829991
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2003 |
|
Journal
|
Hepatology (Baltimore, Md.) |
|
Title
|
Week 48 resistance surveillance in two phase 3 clinical studies of adefovir dipivoxil for chronic hepatitis B. |
|
Author
|
Westland CE,Yang H,Delaney WE 4th,Gibbs CS,Miller MD,Wulfsohn M,Fry J,Brosgart CL,Xiong S,437 and 438 Study Teams. |
|
Evidence
|
The natural polymorphismrtF221Y occurred at the highest frequency (1.6%, 8 of498 genotyped patients).
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HBV Mutation Detail Information