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HBV Mutation Detail Information

> T473C Search Result


Mutation Information
Mutation Site T473C
Mutation Type Nucleotide level
Gene/Protein/Region Type S
Nucleotide_Mutation C107R
Genotype/Subtype C
Viral Reference M12906
Country China
Literature Information
PubMed PMID 19272629
Clinical information Yes
Disease HBV infection
Published Year 2009
Journal Virology
Title Association between genomic heterogeneity of hepatitis B virus and intrauterine infection.
Author Cheng H,Su H,Wang S,Shao Z,Men K,Li M,Li S,Zhang J,Xu J,Zhang H,Yan Y,Xu D
Evidence Five of these six mutations may be mainly divided into two types: (1) C3116T and C705T mutations, which were detected in all clones isolated from group C, but emerged with lower proportions in groups M and N; and (2) C3175T, C96T and T473C mutations, which were detected in clones isolated from one mother (M4) in group M and four infected neonates (N2, 3, 7 and 8) in group N, but not in clones isolated from mothers in group C.
Mutation Site T473C
Mutation Type Nucleotide level
Gene/Protein/Region Type RT
Nucleotide_Mutation L461S
Genotype/Subtype C
Viral Reference M12906
Country China
Literature Information
PubMed PMID 19272629
Clinical information Yes
Disease HBV infection
Published Year 2009
Journal Virology
Title Association between genomic heterogeneity of hepatitis B virus and intrauterine infection.
Author Cheng H,Su H,Wang S,Shao Z,Men K,Li M,Li S,Zhang J,Xu J,Zhang H,Yan Y,Xu D
Evidence Resulted in substitutions of residues L461S and Y470N, respectively, in the reverse transcriptase domain.
Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation