|
Mutation Information
|
Mutation Site
|
L180M |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Combined Mutation
|
rt.M204V+rt.L180M |
|
Relevant Drug
|
lamivudine (LAM) |
|
Country
|
Spain |
Literature Information
|
PubMed PMID
|
15544736
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2004 |
|
Journal
|
Gastroenterologia y hepatologia |
|
Title
|
[Determination of hepatitis B virus genotype and detection of lamivudine-resistance mutations]. |
|
Author
|
Nogales MC,Serrano MC,Suárez E,Corpas R,Pérez L,Claro R,Jarana R,Romero-Gómez M,Martín-Mazuelos E |
|
Evidence
|
Patients with genotype A showed the pattern M204I+WT in the first 12 months and those with genotype D showed the pattern L180M+M204V with or without WT at 18 months.
|
|
|
HBV Mutation Detail Information