HBV Mutation Detail Information

> V191I Search Result


Mutation Information
Mutation Site V191I
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Genotype/Subtype C
Relevant Drug tenofovir (TDF)
Country Korea
Literature Information
PubMed PMID 24836314
Disease Chronic hepatitis B
Published Year 2014
Journal Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology
Title Viral evolutionary changes during tenofovir treatment in a chronic hepatitis B patient with sequential nucleos(t)ide therapy.
Author Lee HW,Chang HY,Yang SY,Kim HJ
Evidence However, this patient experienced virological breakthrough under TDF with a HBV strain bearing rtL80M, rtL180M, rtM204V/I, rtA200V, rtF221Y, rtS223A, rtT184A/L, rtR153Q, and rtV191I combined mutations without rtA194T mutation.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation