Mutation Information
Mutation Site
|
V191I |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
RT |
Genotype/Subtype
|
C |
Relevant Drug
|
tenofovir (TDF) |
Country
|
Korea |
Literature Information
PubMed PMID
|
24836314
|
Disease
|
Chronic hepatitis B
|
Published Year
|
2014 |
Journal
|
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology |
Title
|
Viral evolutionary changes during tenofovir treatment in a chronic hepatitis B patient with sequential nucleos(t)ide therapy. |
Author
|
Lee HW,Chang HY,Yang SY,Kim HJ |
Evidence
|
However, this patient experienced virological breakthrough under TDF with a HBV strain bearing rtL80M, rtL180M, rtM204V/I, rtA200V, rtF221Y, rtS223A, rtT184A/L, rtR153Q, and rtV191I combined mutations without rtA194T mutation.
|
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