|
Mutation Information
|
Mutation Site
|
V173L |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
adefovir (ADV) |
Literature Information
|
PubMed PMID
|
19152409
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2009 |
|
Journal
|
Journal of medical virology |
|
Title
|
Association of lamivudine-resistant mutational patterns with the antiviral effect of adefovir in patients with chronic hepatitis B. |
|
Author
|
Cha CK,Kwon HC,Cheong JY,Cho SW,Hong SP,Kim SO,Yoo WD |
|
Evidence
|
In addition to the YMDD mutations, the rtL180M, rtL80I, and rtV173L mutations were also present in 78%, 43%, and 11% of patients, respectively.
|
|
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HBV Mutation Detail Information