|
Mutation Information
|
Mutation Site
|
T184S |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
entecavir (ETV) |
|
Country
|
Zambia and South Africa |
Literature Information
|
PubMed PMID
|
23892239
|
|
Disease
|
HBV-HIV coinfection
|
|
Published Year
|
2013 |
|
Journal
|
Journal of acquired immune deficiency syndromes (1999) |
|
Title
|
HIV-HBV coinfection in Southern Africa and the effect of lamivudine- versus tenofovir-containing cART on HBV outcomes. |
|
Author
|
Hamers RL,Zaaijer HL,Wallis CL,Siwale M,Ive P,Botes ME,Sigaloff KC,Hoepelman AI,Stevens WS,Rinke de Wit TF,PharmAccess African Studies to Evaluate Resistance (PASER). |
|
Evidence
|
Two individuals had a mutation in HBV pol associated with resistance to entecavir (I169L, T184S).
|
|
|
HBV Mutation Detail Information