HBV Mutation Detail Information

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Mutation Information
Mutation Site M204L
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Combined Mutation rt.M204L+rt.L180M
Genotype/Subtype C
Relevant Drug lamivudine (LAM)
Country Japan
Literature Information
PubMed PMID 15338371
Disease Chronic hepatitis B
Published Year 2004
Journal Journal of gastroenterology
Title Prognostic indicators of breakthrough hepatitis during lamivudine monotherapy for chronic hepatitis B virus infection.
Author Tanaka Y,Yeo AE,Orito E,Ito K,Hirashima N,Ide T,Sata M,Mizokami M
Evidence Univariate statistical analyses showed that possible prognostic indicators for the occurrence of BTH were pre-S deletions ( P = 0.03) and L180M/M204L mutations ( P = 0.04).

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation