|
Mutation Information
|
Mutation Site
|
L180M |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
lamivudine (LAM) |
|
Country
|
South African |
Literature Information
|
PubMed PMID
|
32545313
|
|
Disease
|
HBV-HIV coinfection;
Chronic hepatitis B;
Occult HBV infection
|
|
Published Year
|
2020 |
|
Journal
|
Viruses |
|
Title
|
Impact of Lamivudine-Based Antiretroviral Treatment on Hepatitis B Viremia in HIV-Coinfected South Africans. |
|
Author
|
Lukhwareni A,Gededzha MP,Amponsah-Dacosta E,Blackard JT,Burnett RJ,Selabe SG,Kyaw T,Mphahlele MJ |
|
Evidence
|
Several lamivudine-associated HBV resistance mutations, including L180M, A181T, M204I, and M204V, were observed.
|
|
|
HBV Mutation Detail Information