|
Mutation Information
|
Mutation Site
|
L180M |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
lamivudine (LAM) |
Literature Information
|
PubMed PMID
|
18605187
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2007 |
|
Journal
|
Medycyna wieku rozwojowego |
|
Title
|
[HBV gene variants and polymerse gene mutations in children with chronic hepatitis B in the course of the antiviral therapy]. |
|
Author
|
Góra-Gebka M,Liberek A,Charmuszko U,Sikorska-Wiśniewska G,Szlagatys-Sidorkiewicz A,Korzon M,Bielawski K |
|
Evidence
|
YIDD mutation appeared to be the single one in the viral polymerase gene, while YVDD mutations in four patients were accompanied by other changes at amino acid sequence of the HBV polymerase: rtL180M, rtN124D and rtL164M.
|
|
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HBV Mutation Detail Information