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Mutation Information
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Mutation Site
|
Q478R |
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Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
P |
Literature Information
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PubMed PMID
|
14752824
|
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Disease
|
Chronic hepatitis B
|
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Published Year
|
2004 |
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Journal
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Hepatology (Baltimore, Md.) |
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Title
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Identification of HBV DNA sequences that are predictive of response to lamivudine therapy. |
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Author
|
Ciancio A,Smedile A,Rizzetto M,Lagget M,Gerin J,Korba B |
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Evidence
|
In our study, there is evidence that S211T (S559T)27 and Q130P (Q478R)25 are not directly associated with drug resistance since, in pretreatment sera, S211T was present in a responder patient and Q130P was present in all 26 individuals.
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HBV Mutation Detail Information