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Mutation Information
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Mutation Site
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N238D |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
|
RT |
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Genotype/Subtype
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B;C |
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Relevant Drug
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adefovir dipivoxil (ADV) |
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Country
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South Korea;China |
Literature Information
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PubMed PMID
|
29713126
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Published Year
|
2018 |
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Journal
|
World journal of gastroenterology |
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Title
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Naturally occurring hepatitis B virus reverse transcriptase mutations related to potential antiviral drug resistance and liver disease progression. |
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Author
|
Choi YM,Lee SY,Kim BJ |
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Evidence
|
A total of 26 types of RT mutations, including rtS53N, rtT54N, rtL82M, rtV84M, rtS85A, rtI91L, rtY126C, rtT128I/N, rtN139D, rtW153Q, rtF166L, rtV191I, rtA200V, rtV207I, rtS213T, rtV214A, rtQ215P/S, rtL217R, rtE218D, rtF221Y, rtL229G/V/W, rtI233V, rtP237H, rtN238D/S/T, rtY245H, and rtS/C256G, are considered putative drug resistance mutations (Category 3) (Table (Table11)
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HBV Mutation Detail Information