Mutation Information
Mutation Site
|
M204I |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
RT |
Relevant Drug
|
lamivudine (LAM) |
Country
|
Korea |
Literature Information
PubMed PMID
|
15932365
|
Disease
|
Chronic hepatitis B
|
Published Year
|
2005 |
Journal
|
Alimentary pharmacology & therapeutics |
Title
|
Changes in different regions of hepatitis B virus gene in hepatitis B 'e' antigen-negative patients with chronic hepatitis B: the effect of long-term lamivudine therapy. |
Author
|
Buti M,Jardi R,Rodriguez-Frias F,Valdes A,Schaper M,Esteban R,Guardia J |
Evidence
|
About 75% of the patients with M204V mutations were responders and none with M204I or mixed pattern sustained response.
|
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