HBV Mutation Detail Information

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Mutation Information
Mutation Site M550V
Mutation Type Amino acid level
Gene/Protein/Region Type P
Relevant Drug lamivudine (LAM)
Literature Information
PubMed PMID 10894274
Disease HBV-HIV coinfection
Published Year 2000
Journal AIDS (London, England)
Title Evolution of lamivudine-resistant hepatitis B virus and HIV-1 in co-infected individuals: an analysis of the CAESAR study. CAESAR co-ordinating committee.
Author Pillay D,Cane PA,Ratcliffe D,Atkins M,Cooper D
Evidence HBV drug resistance mutations emerged in five of the 13 patients, four with L526M/M550V (in one of these cases an M550M/V and L526L/M mixture was noted) and one with M550I, however, their HBV viral load at week 52 remained a median of 40-fold lower than baseline values.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation