|
Mutation Information
|
Mutation Site
|
M552I |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
P |
|
Relevant Drug
|
lamivudine (LAM) |
Literature Information
|
PubMed PMID
|
14675262
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2003 |
|
Journal
|
Journal of gastroenterology and hepatology |
|
Title
|
Evolution of wild type and mutants of the YMDD motif of hepatitis B virus polymerase during lamivudine therapy. |
|
Author
|
Zhang X,Liu C,Gong Q,Zhang S,Zhang D,Lu Z,Wang Y |
|
Evidence
|
M552I was detected before therapy in one patient but M552V became the domain strain after therapy.
|
|
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HBV Mutation Detail Information