Mutation Information
Mutation Site
|
M204I |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
RT |
Genotype/Subtype
|
D |
Relevant Drug
|
lamivudine (LAM) |
Country
|
Iran |
Literature Information
PubMed PMID
|
19586679
|
Disease
|
HBV infection
|
Published Year
|
2009 |
Journal
|
Journal of hepatology |
Title
|
Prevalence, viral replication efficiency and antiviral drug susceptibility of rtQ215 polymerase mutations within the hepatitis B virus genome. |
Author
|
Amini-Bavil-Olyaee S,Herbers U,Mohebbi SR,Sabahi F,Zali MR,Luedde T,Trautwein C,Tacke F |
Evidence
|
Replication-competent HBV constructs containing the naturally occurring rtQ215H, rtQ215P and rtQ215S mutations were generated, and compared to wild-type, LAM- (rtM204I, rtL180M/rtM204V) and ADV-resistant (rtN236T) clones.
|
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