HBV Mutation Detail Information

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Mutation Information

Mutation Site	T184G
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Genotype/Subtype	A
Relevant Drug	entecavir (ETV)

Literature Information

PubMed PMID	20887378
Published Year	2011
Journal	Journal of viral hepatitis
Title	Impact of hepatitis B e antigen-suppressing mutations on the replication efficiency of entecavir-resistant hepatitis B virus strains.
Author	Amini-Bavil-Olyaee S,Herbers U,Luedde T,Trautwein C,Tacke F
Evidence	To comprehensively analyse the impact of PC or BCP mutations on viral replication of ETV-resistant HBV mutants, replication-competent HBV constructs were generated harbouring lamivudine resistance (rtM204V/rtL180M, rtM204I) plus ETV resistance (rtS202G, rtS202I or rtT184G) on wild-type (WT)-, PC- and BCP-backgrounds.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation