HBV Mutation Detail Information

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Mutation Information
Mutation Site N236T
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Combined Mutation rt.N236T+rt.A181T;rt.N236T+rt.A181V
Genotype/Subtype D
Relevant Drug adefovir (ADV)
Country Caucasian
Literature Information
PubMed PMID 19065672
Clinical information Yes
Disease Chronic hepatitis B
Published Year 2009
Journal Hepatology (Baltimore, Md.)
Title Complex dynamics of hepatitis B virus resistance to adefovir.
Author Pallier C,Rodriguez C,Brillet R,Nordmann P,Hézode C,Pawlotsky JM
Evidence UNLABELLED: In patients with hepatitis B e antigen-negativeChronic hepatitis B, adefovir dipivoxil administration selects variants bearing reverse transcriptase rtN236T and/or rtA181V/T substitutions in 29% of cases after 5 years.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation