Mutation Information
Mutation Site
|
L164M |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
RT |
Combined Mutation
|
rt.I266V+rt.D263E+rt.L235F+rt.Q215S+rt.S176W+rt.L164M;rt.I266V+rt.D263E+rt.M204V+rt.L180M+rt.L164M+rt.T128A+rt.F122L;rt.K266V+rt.R266V+rt.I266V+rt.Y257H+rt.Q215H+rt.V214A+rt.V207I+rt.I187L+rt.V173L+rt.L164M+rt.F122L;rt.S259A+rt.M250V+rt.M204V+rt.L180M+rt.L164M+rt.V142E+rt.T128I |
Genotype/Subtype
|
D |
Relevant Drug
|
lamivudine (LAM);adefovir dipivoxil (ADV);entecavir (ETV) |
Country
|
Rome |
Literature Information
PubMed PMID
|
19442845
|
Disease
|
Chronic hepatitis B
|
Published Year
|
2009 |
Journal
|
Journal of virological methods |
Title
|
A sensitive direct sequencing assay based on nested PCR for the detection of HBV polymerase and surface glycoprotein mutations. |
Author
|
Vincenti D,Solmone M,Garbuglia AR,Iacomi F,Capobianchi MR |
Evidence
|
Table 1
|
|
|