HBV Mutation Detail Information

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Mutation Information

Mutation Site	V173L
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Genotype/Subtype	C2
Country	Korea

Literature Information

PubMed PMID	20332649
Disease	Chronic hepatitis B
Published Year	2010
Journal	Intervirology
Title	Response to adefovir depends on mutation patterns in precore region, basal core promoter and reverse transcriptase, and on-treatment responses in Lamivudine-resistant chronic hepatitis B patients.
Author	Song BC,Cui XJ,Shin JW,Park NH,Cho YK,Song HJ,Hyun S,Jeong SU,Choi EK,Kim HU
Evidence	PC mutation, the absence of compensatory mutations (rtL80I/V or rtV173L), and a decrease in serum hepatitis B virus (HBV) DNA by 3 log or greater at 6 months were independent predictors of virologic response.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation