Mutation Information
Mutation Site
|
T184L |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
RT |
Combined Mutation
|
rt.M204I+rt.T184L+rt.L180M |
Relevant Drug
|
lamivudine (LAM);adefovir (ADV) |
Country
|
China |
Literature Information
PubMed PMID
|
19302908
|
Disease
|
Chronic hepatitis B
|
Published Year
|
2009 |
Journal
|
Clinical therapeutics |
Title
|
Evolution of hepatitis B virus polymerase mutations in a patient with HBeAg-positive chronic hepatitis B virus treated with sequential monotherapy and add-on nucleoside/nucleotide analogues. |
Author
|
Wang F,Wang H,Shen H,Meng C,Weng X,Zhang W |
Evidence
|
The rtM204I mutation was associated with compensatory mutations (rtL180M and rtT184L).
|
|
|