|
Mutation Information
|
Mutation Site
|
N248H |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Genotype/Subtype
|
F2;A2 |
|
Viral Reference
|
X02763
|
|
Relevant Drug
|
adefovir (ADV) |
|
Country
|
Brazil |
Literature Information
|
PubMed PMID
|
27787680
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2017 |
|
Journal
|
Archives of virology |
|
Title
|
Identification of a new hepatitis B virus recombinant D2/D3 in the city of São Paulo, Brazil. |
|
Author
|
Santana LC,Mantovani NP,Ferreira MC,Arnold R,Duro RL,Ferreira PR,Hunter JR,Leal É,Diaz RS,Komninakis SV |
|
Evidence
|
Mutations related to adefovir resistance, such as rtN248H and rtL217R, are polymorphisms related to genotypes, and they have been found in all the sequences from the F2 and A2 genotypes, respectively.
|
|
|
HBV Mutation Detail Information