|
Mutation Information
|
Mutation Site
|
I269L |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
tenofovir (TDF);adefovir (ADV) |
|
Country
|
USA |
Literature Information
|
PubMed PMID
|
24118725
|
|
Disease
|
HBV infection
|
|
Published Year
|
2014 |
|
Journal
|
Liver international : official journal of the International Association for the Study of the Liver |
|
Title
|
HBV clinical isolates expressing adefovir resistance mutations show similar tenofovir susceptibilities across genotypes B, C and D. |
|
Author
|
Liu Y,Miller MD,Kitrinos KM |
|
Evidence
|
Of these, four amino acids were unique to patient 2 compared to the consensus sequence (rtY124H, rtT128A, rtI269L, rtA317S).
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|
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HBV Mutation Detail Information