HBV Mutation Detail Information

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Mutation Information
Mutation Site T184I
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Genotype/Subtype D
Relevant Drug lamivudine (LAM)
Country Italy
Literature Information
PubMed PMID 23026293
Disease Chronic hepatitis B
Published Year 2012
Journal Antiviral research
Title Genotype-specific mutations in the polymerase gene of hepatitis B virus potentially associated with resistance to oral antiviral therapy.
Author Mirandola S,Sebastiani G,Rossi C,Velo E,Erne EM,Vario A,Tempesta D,Romualdi C,Campagnolo D,Alberti A
Evidence In genotype D infected patients, seven mutations at five positions (rtL80I/V, rtV173L, rtL180M, rtT184I, rt204I/V) were significantly associated with LAM therapy (Fisher’s exact test; Benjamini–Hochberg adjusted p value < 0.05).

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation