|
Mutation Information
|
Mutation Site
|
M250I |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Genotype/Subtype
|
D |
|
Relevant Drug
|
entecavir (ETV) |
Literature Information
|
PubMed PMID
|
20169198
|
|
Published Year
|
2010 |
|
Journal
|
PloS one |
|
Title
|
Mechanistic characterization and molecular modeling of hepatitis B virus polymerase resistance to entecavir. |
|
Author
|
Walsh AW,Langley DR,Colonno RJ,Tenney DJ |
|
Evidence
|
Several different ETVr substitutions have been observed in ETV-treated patients, including T184A/C/F/G/I/L/M/S, S202C/G/I, and M259 I/L/V.
|
|
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HBV Mutation Detail Information