Mutation Information
Mutation Site
|
L80I |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
RT |
Relevant Drug
|
lamivudine (LAM) |
Literature Information
PubMed PMID
|
20875460
|
Published Year
|
2010 |
Journal
|
Antiviral research |
Title
|
Hepatitis B virus reverse transcriptase sequence variant database for sequence analysis and mutation discovery. |
Author
|
Rhee SY,Margeridon-Thermet S,Nguyen MH,Liu TF,Kagan RM,Beggel B,Verheyen J,Kaiser R,Shafer RW |
Evidence
|
Among the 10 well-characterized N(t)RTI-resistance mutations, L80I/V, V173L, L180M, A181T, T184S, S202G and M204I/V were significantly associated with treatment with lamivudine, an L-nucleoside analog
|
|
|