HBV Mutation Detail Information

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Mutation Information
Mutation Site M204V
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Combined Mutation rt.N236T+rt.M204V+rt.S202G+rt.A181V+rt.L180M
Genotype/Subtype C
Relevant Drug lamivudine (LAM);adefovir (ADV);telbivudine (LDT);entecavir (ETV)
Country China
Literature Information
PubMed PMID 21392168
Disease Chronic hepatitis B; Liver cirrhosis
Published Year 2011
Journal Journal of viral hepatitis
Title Genotypic resistance profile of hepatitis B virus (HBV) in a large cohort of nucleos(t)ide analogue-experienced Chinese patients with chronic HBV infection.
Author Liu Y,Wang C,Zhong Y,Li X,Dai J,Ren X,Xu Z,Li L,Yao Z,Ji D,Wang L,Zhang L,Wong VW,Zoulim F,Xu D
Evidence Multidrug-resistant HBV strains were identified in eight patients, including two novel strains with mutational patterns rtL180M + A181V + S202G + M204V + N236T and rtL180M + S202G + M204V + N236T.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation