Mutation Information
Mutation Site
|
V75I |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
RT |
Literature Information
PubMed PMID
|
28396546
|
Published Year
|
2017 |
Journal
|
Antimicrobial agents and chemotherapy |
Title
|
Structural Insights into HIV Reverse Transcriptase Mutations Q151M and Q151M Complex That Confer Multinucleoside Drug Resistance. |
Author
|
Das K,Martinez SE,Arnold E |
Evidence
|
Q151M and four associated mutations, A62V, V75I, F77L, and F116Y, were detected in patients failing therapies with dideoxynucleosides (didanosine [ddI], zalcitabine [ddC]) and/or zidovudine (AZT).
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