HBV Mutation Detail Information

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Mutation Information
Mutation Site A181T
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Combined Mutation rt.N236T+rt.A181T
Relevant Drug lamivudine (LAM);adefovir (ADV)
Literature Information
PubMed PMID 18331765
Disease HBV infection
Published Year 2008
Journal Journal of hepatology
Title Impact of hepatitis B virus rtA181V/T mutants on hepatitis B treatment failure.
Author Villet S,Pichoud C,Billioud G,Barraud L,Durantel S,Trépo C,Zoulim F
Evidence In this study, we characterized the main variants harboring the rtA181T/V mutation isolated from 10 consecutive patients who developed lamivudine and/or adefovir resistance.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation