HBV Mutation Detail Information

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Mutation Information
Mutation Site S137Q
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Literature Information
PubMed PMID 30179704
Published Year 2018
Journal Virus research
Title Amino acid substitutions Q129N and T131N/M133T in hepatitis B surface antigen (HBsAg) interfere with the immunogenicity of the corresponding HBsAg or viral replication ability.
Author Kang Y,Li F,Guo H,Yang S,Zhang Y,Zhu H,Wang J,Mao R,Qin Y,Xu J,Chen X,Wu C,Zhang J
Evidence For the overlapping open reading frame of S and reverse transcriptase (rt) region, the substitutions Q129 N and T131 N/M133 T result in the substitutions rt S137Q and rt N139 K in the RT region.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation