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Mutation Information
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Mutation Site
|
M204I |
|
Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
RT |
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Combined Mutation
|
rt.M204I+rt.L80I;rt.M250L+rt.M204I;rt.M204I+rt.L180M+rt.L80I;rt.M204I+rt.L180M |
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Relevant Drug
|
lamivudine (LAM);telbivudine (LDT);entecavir (ETV);adefovir dipivoxil (ADV) |
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Country
|
China |
Literature Information
|
PubMed PMID
|
27694733
|
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Disease
|
Chronic hepatitis B
|
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Published Year
|
2016 |
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Journal
|
Journal of infection in developing countries |
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Title
|
Monitoring of genotypic resistance profile in chronic hepatitis B patients receiving nucleos(t)ide analogues in Huzhou, China. |
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Author
|
Qian F,Qin J,Li D,Ma Z,Zhang H,Jin F,Wang W |
|
Evidence
|
Among patients who harbored rtM204 combination mutations, rtM204I and rtM204V were significantly associated with rtL80I/V and rtL180M, respectively.
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HBV Mutation Detail Information