HBV Mutation Detail Information

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Mutation Information
Mutation Site N118D
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Genotype/Subtype D
Viral Reference GQ183486.1
Country Iran
Literature Information
PubMed PMID 27882062
Disease HBV infection
Published Year 2016
Journal Hepatitis monthly
Title Genotyping and Mutation Pattern in the Overlapping MHR Region of HBV Isolates in Southern Khorasan, Eastern Iran.
Author Ziaee M,Javanmard D,Sharifzadeh G,Hasan Namaei M,Azarkar G
Evidence The most amino acid substitutions of surface protein were Q129H (34.42%) and A168V (8.2%), other escape mutants observed in this study were P127L/T, S117G, T125M, S143L, D144E and E164D. In the RT gene, Q149K was the most frequently identified amino acid substitution (9.83%), followed by L122F (8.19%), N118D/T (6.55%), L157M (4.91%), and H124Y (3.27%).

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation