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Mutation Information
|
Mutation Site
|
M204I |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Combined Mutation
|
rt.M204I+rt.V173L;rt.M204I+rt.V173L+rt.M129L;rt.H337N+rt.M204I+rt.V173L+rt.M129L |
|
Genotype/Subtype
|
C2 |
|
Country
|
South Korea |
Literature Information
|
PubMed PMID
|
26322642
|
|
Published Year
|
2015 |
|
Journal
|
PloS one |
|
Title
|
Substitution at rt269 in Hepatitis B Virus Polymerase Is a Compensatory Mutation Associated with Multi-Drug Resistance. |
|
Author
|
Ahn SH,Kim DH,Lee AR,Kim BK,Park YK,Park ES,Ahn SH,Shin GC,Park S,Kang HS,Rhee JK,Yang SI,Chong Y,Kim KH |
|
Evidence
|
We have previously reported a multi-drug resistant HBV mutant (clone 50–2), which harbored the quintuple rtM129L+V173L+M204I+L269I+H337N mutations in the RT domain [15].
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HBV Mutation Detail Information