|
Mutation Information
|
Mutation Site
|
A181T |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Viral Reference
|
X70185
|
|
Relevant Drug
|
adefovir (ADV) |
|
Country
|
China |
Literature Information
|
PubMed PMID
|
17913933
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2007 |
|
Journal
|
Journal of clinical microbiology |
|
Title
|
Evolution of primary and compensatory lamivudine resistance mutations in chronic hepatitis B virus-infected patients during long-term lamivudine treatment, assessed by a line probe assay. |
|
Author
|
Libbrecht E,Doutreloigne J,Van De Velde H,Yuen MF,Lai CL,Shapiro F,Sablon E |
|
Evidence
|
M204I mutations in combination with L80I were often detected by sequencing during weeks 24 and 52, while LiPA frequently found the former combination as well as A181T mutations and combinations at weeks 12, 24, and 52.
|
|
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HBV Mutation Detail Information