HBV Mutation Detail Information

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Mutation Information
Mutation Site Q177H
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Genotype/Subtype E
Country Angola
Literature Information
PubMed PMID 24632784
Disease HBV infection
Published Year 2014
Journal PloS one
Title Analysis of complete nucleotide sequences of Angolan hepatitis B virus isolates reveals the existence of a separate lineage within genotype E.
Author Lago BV,Mello FC,Ribas FS,Valente F,Soares CC,Niel C,Gomes SA
Evidence Five specific mutations, namely small S protein T57I, polymerase Q177H, G245W and M612L, and X protein V30L, were observed in 79-96% of the isolates of the separate lineage, compared to a frequency of 0-12% among the other HBV/E African isolates.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation