HBV Mutation Detail Information

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Mutation Information

Mutation Site	L180M
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Combined Mutation	rt.L180M+rt.M204V+rt.M204I;rt.L180M+rt.M204V+rt.T184S;rt.M204V+rt.L180M+rt.V173L;rt.L180M+rt.M204V+rt.M204I+rt.Q215S;rt.L180M+rt.M204S;rt.M204V+rt.L180M+rt.V173L+rt.I169T
Relevant Drug	adefovir (ADV);lamivudine (LAM)

Literature Information

PubMed PMID	16673294
Published Year	2006
Journal	Seminars in liver disease
Title	Antiviral drug resistance: clinical consequences and molecular aspects.
Author	Bartholomeusz A,Locarnini SA
Evidence	In contrast, resistance to adefovir is associated with mutations at rtN236T +/- rtA181V.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation