Mutation Information
Mutation Site
|
M204V |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
RT |
Relevant Drug
|
lamivudine (LAM) |
Country
|
USA |
Literature Information
PubMed PMID
|
22510694
|
Disease
|
HBV infection
|
Published Year
|
2012 |
Journal
|
Nature communications |
Title
|
Convergence and coevolution of hepatitis B virus drug resistance. |
Author
|
Thai H,Campo DS,Lara J,Dimitrova Z,Ramachandran S,Xia G,Ganova-Raeva L,Teo CG,Lok A,Khudyakov Y |
Evidence
|
Treatment with lamivudine of patients infected with hepatitis B virus (HBV) results in a high rate of drug resistance, which is primarily associated with the rtM204I/V substitution in the HBV reverse transcriptase domain.
|
|
|