HBV Mutation Detail Information

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Mutation Information

Mutation Site	S116T
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Combined Mutation	rt.S116T+s.C107*
Relevant Drug	lamivudine (LAM);adefovir (ADV);hepatitis B immunoglobulin (HBIG)
Country	Haiti

Literature Information

PubMed PMID	17030194
Disease	Chronic hepatitis B; Liver cirrhosis
Published Year	2006
Journal	Gastroenterology
Title	Selection of a multiple drug-resistant hepatitis B virus strain in a liver-transplanted patient.
Author	Villet S,Pichoud C,Villeneuve JP,Trépo C,Zoulim F
Evidence	These mutations within S protein lead to rtT128I and rtS116T substitutions respectively in RT protein (Table 1).

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation