HBV Mutation Detail Information

> L528M Search Result


Mutation Information
Mutation Site L528M
Mutation Type Amino acid level
Gene/Protein/Region Type P
Genotype/Subtype A;C;D
Relevant Drug famciclovir (FCV)
Literature Information
PubMed PMID 11050059
Clinical information Yes
Disease Chronic hepatitis B
Published Year 2000
Journal Hepatology (Baltimore, Md.)
Title Early detection of viral resistance by determination of hepatitis B virus polymerase mutations in patients treated by lamivudine for chronic hepatitis B.
Author Nafa S,Ahmed S,Tavan D,Pichoud C,Berby F,Stuyver L,Johnson M,Merle P,Abidi H,Trépo C,Zoulim F
Evidence Determination of viral genotype, precore mutants, and polymerase gene mutants (L528M, M552V, M552I) was performed using the research version of Lipa-HBV.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation