Mutation Information
Mutation Site
|
L528M |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
P |
Genotype/Subtype
|
A;C;D |
Relevant Drug
|
famciclovir (FCV) |
Literature Information
PubMed PMID
|
11050059
|
Clinical information
|
Yes
|
Disease
|
Chronic hepatitis B
|
Published Year
|
2000 |
Journal
|
Hepatology (Baltimore, Md.) |
Title
|
Early detection of viral resistance by determination of hepatitis B virus polymerase mutations in patients treated by lamivudine for chronic hepatitis B. |
Author
|
Nafa S,Ahmed S,Tavan D,Pichoud C,Berby F,Stuyver L,Johnson M,Merle P,Abidi H,Trépo C,Zoulim F |
Evidence
|
Determination of viral genotype, precore mutants, and polymerase gene mutants (L528M, M552V, M552I) was performed using the research version of Lipa-HBV.
|
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