Mutation Information
Mutation Site
|
G700A |
Mutation Type
|
Nucleotide level |
Gene/Protein/Region Type
|
RT |
Nucleotide_Mutation
|
V191I |
Country
|
china |
Literature Information
PubMed PMID
|
33124952
|
Disease
|
Chronic hepatitis B
|
Published Year
|
2020 |
Journal
|
Emerging microbes & infections |
Title
|
Mutational characterization of HBV reverse transcriptase gene and the genotype-phenotype correlation of antiviral resistance among Chinese chronic hepatitis B patients. |
Author
|
Fu Y,Wu S,Hu Y,Chen T,Zeng Y,Liu C,Ou Q |
Evidence
|
After scrutinizing the frequency of mutations within these sites, only two NA-r mutations, ntG700A (rtV191I, P = 0.014) and ntC671T (rtA181T/V, P = 0.048) from treatment-naive and post-treatment samples, respectively, were identified as genotype-specific mutations (Figure 3(C–D)).
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